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ISPOR 2012
23 April 2012

Brendan Mulhern to attend ISPOR's 17th Annual International Meeting in Washington

Brendan Mulhern (University of Sheffield) will be presenting the latest findings from collaborative research on the development of a shorter version of the Diabetes Health Profile (DHP-12).

MEASURING HEALTH RELATED QUALITY OF LIFE IN DIABETES:

THE VALIDATION OF THE DIABETES HEALTH PROFILE (DHP-18) AND THE DEVELOPMENT OF A BRIEF MEASURE OF DIABETES RELATED HRQL (DHP-12)

Brendan Mulhern, Health Economics and Decision Science, University of Sheffield; Dr Keith Meadows DHP Research & Consultancy Ltd
  • Objectives: The Diabetes Health Profile (DHP-18) is widely used as a measure of health related quality of life in diabetes. The aims of this study is to validate the three domain conceptual framework of the DHP-18, and subsequently use Rasch and psychometric analysis to develop a brief version of the diabetes health profile (DHP-12) that has strong psychometric performance and covers the same conceptual framework as the DHP-18.
  • Methods: Factor analysis was used to investigate the three domain conceptual framework of the DHP-18. Item level psychometric analysis and subsequently Rasch analysis was used to select items for the brief DHP-6/9/12 and compare the performance of the 2 instruments. The data used was from a longitudinal study of HRQL in diabetes.
  • Results: The conceptual framework of the DHP-18 including domains of psychological distress, barriers to activity and disinhibited eating was confirmed. Rasch analysis selected the four strongest items for each domain to produce the DHP-12. The DHP-12 was found to be correlated with the DHP-18, and perform at a similar level.
  • Conclusions: The DHP-12 is a valid measure of HRQL in diabetes that can be used as a brief instrument. The measure is psychometrically comparable to the longer DHP-18, and can therefore be used in place of this instrument to lower the burden on people with diabetes.

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